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| 4 || '''Mood, stress & sleep''' || Magnesium, B1, B3, B6, B12, biotin, folate, vitamin C ''(normal psychological function)'' || [[Ashwagandha]], saffron, [[L-Theanine|L-theanine]] (NF - unless from green tea), [[5-HTP]] (NF - unless <30% from Griffonia seed), [[valerian]] (THR), chamomile, lemon balm, [[GABA]] (Med), tart cherry, [[melatonin]] (Med) || Magnesium (glycinate/bisglycinate) is the standout ingredient. Melatonin is medicinal in the UK.
| 4 || '''Mood, stress & sleep''' || Magnesium, B1, B3, B6, B12, biotin, folate, vitamin C ''(normal psychological function)'' || [[Ashwagandha]], saffron, [[L-Theanine|L-theanine]] (NF - unless from green tea), [[5-HTP]] (NF - unless <30% from Griffonia seed), [[valerian]] (THR), chamomile, lemon balm, [[GABA]] (Med), tart cherry, [[melatonin]] (Med) || Magnesium (glycinate/bisglycinate) is the standout ingredient. Melatonin is medicinal in the UK.
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| 5 || '''Digestive / gut''' || Calcium ''(normal function of digestive enzymes)'', riboflavin, niacin, biotin ''(normal mucous membranes)'' || [[Probiotics]], [[prebiotics]] (inulin, FOS, GOS), [[postbiotics]], digestive [[enzymes]], psyllium, ginger, peppermint, glutamine, triphala. || Strain-specific probiotics, and the gut linked to brain, skin and immunity (the "gut-X axis"). Triphala is an [[Ayurvedic]] blend of amla, haritaki and bibhitaki, traditionally used for digestion and regularity.
| 5 || '''Digestive / gut''' || Calcium ''(normal function of digestive enzymes)'', riboflavin, niacin, biotin ''(normal mucous membranes)'' || [[Probiotics]], [[prebiotics]] (inulin, FOS, GOS, MOS, XOS), [[postbiotics]], digestive [[enzymes]], psyllium, ginger, peppermint, glutamine, triphala. || Strain-specific probiotics, and the gut linked to brain, skin and immunity (the "gut-X axis"). Triphala is an [[Ayurvedic]] blend of amla, haritaki and bibhitaki, traditionally used for digestion and regularity.
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| 6 || '''Women's health''' (by life stage) || B6 ''(regulation of hormonal activity)'', folic acid ''(maternal tissue growth in pregnancy)'', iron, vitamin D, calcium, iodine || ''Menstrual / PMS:'' [[Agnus Castus|Agnus castus]] (Med), evening primrose oil, d-chiro inositol (PCOS/PMOS)<br />''Menopause:'' sage, red clover, [[Black Cohosh|black cohosh]] (THR), soy isoflavones, saffron, [[maca]], shatavari.<br />''Urinary:'' cranberry, D-mannose || Fast growth in perimenopause and menopause products, and "life-stage" ranges. Shatavari (''Asparagus racemosus'') is an [[Ayurvedic]] root promoted for female hormonal balance, menopause and lactation.
| 6 || '''Women's health''' (by life stage) || B6 ''(regulation of hormonal activity)'', folic acid ''(maternal tissue growth in pregnancy)'', iron, vitamin D, calcium, iodine || ''Menstrual / PMS:'' [[Agnus Castus|Agnus castus]] (Med), evening primrose oil, d-chiro inositol (PCOS/PMOS)<br />''Menopause:'' sage, red clover, [[Black Cohosh|black cohosh]] (THR), soy isoflavones, saffron, [[maca]], shatavari.<br />''Urinary:'' cranberry, D-mannose || Fast growth in perimenopause and menopause products, and "life-stage" ranges. Shatavari (''Asparagus racemosus'') is an [[Ayurvedic]] root promoted for female hormonal balance, menopause and lactation.
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! Ingredient !! Area(s) !! Status on G&G Cloud
! Ingredient !! Area(s) !! Status on G&G Cloud
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| [[Agnus Castus|Agnus castus]] || Women's health || Medicinal (MHRA). Should not be sold.
| [[Agnus Castus|Agnus castus]] || Women's health || Medicinal / THR
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|-
| [[Black Cohosh|Black cohosh]] || Women's health || THR
| [[Black Cohosh|Black cohosh]] || Women's health || THR
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| [[Devil's Claw|Devil's claw]] || Joints || THR
| [[Devil's Claw|Devil's claw]] || Joints || THR
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|-
| [[GABA]] || Sleep / stress || Medicinal. Cannot be used by G&G.
| [[GABA]] || Sleep / stress || Medicinal.
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| [[Melatonin]] || Sleep || Medicinal in the UK
| [[Melatonin]] || Sleep || Medicinal in the UK
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| [[Huperzine A]], [[Alpha GPC]] || Cognitive || Medicinal (Alpha GPC Novel Food application in progress)
| [[Huperzine A]], [[Alpha GPC]] || Cognitive || Medicinal (Alpha GPC Novel Food application in progress)
|-
|-
| [[Berberine]] || Metabolic || Novel Food and Medicinal
| [[Berberine]] || Metabolic || Novel Food / Medicinal - under EU scrutiny.
|-
|-
| [[5-HTP]] || Mood / sleep || Griffonia seed powder or extract (max. 30% 5-HTP) only. Synthetic 5-HTP is novel.
| [[5-HTP]] || Mood / sleep || Griffonia seed powder or extract (max. 30% 5-HTP) only. Synthetic 5-HTP is novel.
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| [[Tongkat Ali]] || Men's health || Novel Food
| [[Tongkat Ali]] || Men's health || Novel Food
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| [[Magnesium L-threonate]] || Cognitive || Approved Novel Food, Magtein brand only (R1775). Trademark agreement needed.
| [[Magnesium L-threonate]] || Cognitive || Approved Novel Food, Magtein brand only. Trademark agreement needed.
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| [[Astaxanthin]] || Ageing / beauty || Whole algae (biomass) is not novel. The oleoresin is an authorised Novel Food with dose limits and warnings.
| [[Astaxanthin]] || Ageing / beauty || Whole algae (biomass) is not novel. The oleoresin is an authorised Novel Food with dose limits and warnings.

Latest revision as of 10:29, 30 October 2026

Reference
Health Areas
G&G Cloud staff reference · last edited 30/10/2026

Supplement health areas (sometimes called "need states" or "health platforms") are the main consumer health benefits that food supplements are positioned around. This page summarises the main areas in the UK and international supplement market as of late 2026. For each area it lists the vitamins, minerals, botanicals and other actives most commonly promoted. It is intended as a starting point for new product development and customer enquiries.

The vitamins and minerals in each area are the ones that carry authorised GB health claims for that benefit (see the GB NHC Register). Botanical claims remain "on hold" in GB. This is why most products pair a "hero" botanical with a vitamin or mineral that carries the legal claim.

Important: several ingredients that are widely promoted in these areas are Novel Food, Medicinal or THR according to this wiki, so G&G cannot sell them, or can sell them only in restricted forms. These are marked in the tables below and summarised under G&G regulatory flags. Always check the individual ingredient page before quoting.

Key to flags: (NF) Novel Food or restricted form · (Med) Medicinal · (THR) Traditional Herbal Registration · (?) not yet assessed on G&G Cloud

The main health areas

The order is a rough guide to market size and activity, not an exact ranking.

# Area Vitamins & minerals (typical GB claim) Botanicals & other actives Current trend notes
1 Immunity Vitamin D, vitamin C, zinc, selenium, vitamin A, B6, B12, folate, copper, iron (normal function of the immune system) Elderberry, echinacea (THR), beta-glucans (yeast/mushroom), probiotics, colostrum, quercetin, pelargonium root (THR) Demand has settled since the COVID peak. Vitamin D remains the UK anchor product.
2 Energy & fatigue B2, B3, B5, B6, B12, folate, vitamin C, iron, magnesium (reduction of tiredness and fatigue) CoQ10, ginseng, rhodiola rosea, cordyceps, creatine, NAD Interest in "brain energy" and in clean energy without caffeine.
3 Cognitive / brain Zinc, iron, iodine (normal cognitive function), B5 (mental performance), omega-3 DHA (normal brain function, 250 mg) Fish oils (DHA), lion's mane, bacopa, ginkgo biloba, L-theanine (NF - unless from green tea), citicoline (NF – approved, Cognizin only), phosphatidylserine, creatine, magnesium l-threonate (NF - approved, Magtein only), alpha GPC (Med), huperzine A (Med) One of the fastest-growing areas. Creatine is spreading from sport into cognition.
4 Mood, stress & sleep Magnesium, B1, B3, B6, B12, biotin, folate, vitamin C (normal psychological function) Ashwagandha, saffron, L-theanine (NF - unless from green tea), 5-HTP (NF - unless <30% from Griffonia seed), valerian (THR), chamomile, lemon balm, GABA (Med), tart cherry, melatonin (Med) Magnesium (glycinate/bisglycinate) is the standout ingredient. Melatonin is medicinal in the UK.
5 Digestive / gut Calcium (normal function of digestive enzymes), riboflavin, niacin, biotin (normal mucous membranes) Probiotics, prebiotics (inulin, FOS, GOS, MOS, XOS), postbiotics, digestive enzymes, psyllium, ginger, peppermint, glutamine, triphala. Strain-specific probiotics, and the gut linked to brain, skin and immunity (the "gut-X axis"). Triphala is an Ayurvedic blend of amla, haritaki and bibhitaki, traditionally used for digestion and regularity.
6 Women's health (by life stage) B6 (regulation of hormonal activity), folic acid (maternal tissue growth in pregnancy), iron, vitamin D, calcium, iodine Menstrual / PMS: Agnus castus (Med), evening primrose oil, d-chiro inositol (PCOS/PMOS)
Menopause: sage, red clover, black cohosh (THR), soy isoflavones, saffron, maca, shatavari.
Urinary: cranberry, D-mannose		 Fast growth in perimenopause and menopause products, and "life-stage" ranges. Shatavari (Asparagus racemosus) is an Ayurvedic root promoted for female hormonal balance, menopause and lactation.
7 Men's health Zinc (normal fertility; normal testosterone levels), selenium (normal spermatogenesis) Saw palmetto (Med in prostate products), lycopene, pumpkin seed, tongkat ali (NF), fenugreek, ashwagandha, pygeum (Med) Men's fertility, testosterone and prostate products.
8 Healthy ageing / longevity Vitamin D (muscle function), B12, vitamin K (bones), vitamin C, vitamin E, zinc, selenium (protection of cells from oxidative stress) CoQ10, resveratrol, nicotinamide riboside (NR), nicotinamide mononucleotide (NF), urolithin A (NF), spermidine, astaxanthin, fisetin (NF), PQQ (approved NF), collagen, creatine Most premium launches are in this area, and many longevity actives are novel.
9 Bone, joint & mobility Calcium, vitamin D, vitamin K, magnesium, manganese (normal bones), vitamin C (collagen formation for cartilage) Glucosamine (max. 1100 mg base), chondroitin, MSM, turmeric/curcumin, boswellia, collagen (incl. type II), eggshell membrane, fish oils, Devil's claw (THR) A mature category that is now framed around "active ageing".
10 Heart / cardiovascular Thiamin (heart function), B6, B12, folate (homocysteine metabolism), potassium (blood pressure), EPA/DHA (heart function, 250 mg) Fish oils, plant sterols and oat beta-glucan (cholesterol claims), CoQ10, garlic, hawthorn, red yeast rice (? currently being banned in EU) Stable demand from an older customer base.
11 Metabolic & weight Chromium (normal blood glucose), zinc (carbohydrate metabolism), glucomannan (weight loss, 3 g/day) Berberine (NF + Med), cinnamon, inositol, green tea extract (pure EGCG is NF), fibres, protein, probiotics, gymnema silvestre (Med), hydroxycitric acid (Med) The biggest new driver is "GLP-1 companion" products for people on Mounjaro or Wegovy, which support protein intake, muscle retention, fibre and gut comfort.
12 Beauty from within Biotin, zinc, selenium (hair, nails), copper (hair and skin pigmentation), vitamin C (collagen formation for skin), vitamin A (skin) Collagen, hyaluronic acid, ceramides, astaxanthin, horsetail / silica, keratin Collagen-led products combined with gut and skin ingredients.

Adjacent areas

  • Eye health: lutein, zeaxanthin, DHA (normal vision), vitamin A, riboflavin, zinc (normal vision).
  • Sports & active nutrition: protein, creatine, electrolytes, beta-alanine, caffeine. This area now overlaps with energy and healthy ageing (muscle retention).

G&G regulatory flags

These ingredients are commonly promoted in the areas above, but this wiki currently records the following restrictions on them. See each page for the detail and the date it was last updated.

Ingredient Area(s) Status on G&G Cloud
Agnus castus Women's health Medicinal / THR
Black cohosh Women's health THR
Valerian Sleep THR
Echinacea, Pelargonium root Immunity THR
Devil's claw Joints THR
GABA Sleep / stress Medicinal.
Melatonin Sleep Medicinal in the UK
Saw palmetto Men's health Medicinal when used in a prostate / men's health product
Huperzine A, Alpha GPC Cognitive Medicinal (Alpha GPC Novel Food application in progress)
Berberine Metabolic Novel Food / Medicinal - under EU scrutiny.
5-HTP Mood / sleep Griffonia seed powder or extract (max. 30% 5-HTP) only. Synthetic 5-HTP is novel.
L-Theanine Cognitive / stress Not novel only when it comes from green tea.
Ashwagandha Stress / men's health Not permitted in Denmark, and restricted case by case in Sweden. Check the destination market.
Tongkat Ali Men's health Novel Food
Magnesium L-threonate Cognitive Approved Novel Food, Magtein brand only. Trademark agreement needed.
Astaxanthin Ageing / beauty Whole algae (biomass) is not novel. The oleoresin is an authorised Novel Food with dose limits and warnings.
Nicotinamide mononucleotide, Urolithin A Ageing Novel Foods. (NMN application in progress).
Fisetin Ageing Pure or purified extracts are novel. Smoke tree bark, leaf and flower are not novel in food supplements.
CDP Choline (Citicoline) Cognitive Approved Novel Food, up to 500 mg per serving. Cognizin only.
PQQ Ageing / energy Approved Novel Food (2020).
EGCG Metabolic Pure EGCG is novel. Green tea extract is acceptable.
Gymnema silvestre, Hydroxycitric acid Metabolic Medicinal (HCA as a purified extract)
Pygeum Men's health Medicinal and endangered. Not used by G&G.
Nicotinamide riboside (NR) Ageing Permitted vitamin form (B3) since 2023
Glucosamine Joints Food supplements must stay below 1100 mg glucosamine base
Rhodiola rosea Energy / stress Limited to 250 mg equivalent. Listed under CITES.
Red yeast rice Heart Under EU scrutiny for Monacolin content, full ban being pushed through for 2027.

References

  1. GB Nutrition and Health Claims (NHC) Register – https://www.gov.uk/government/publications/great-britain-nutrition-and-health-claims-nhc-register
  2. NutraIngredients – Forces and factors that fuelled the supplement industry in 2025 – https://www.nutraingredients.com/Article/2026/01/05/forces-and-factors-that-fueled-the-supplement-industry-in-2025
  3. NutraIngredients – GLP-1, longevity and mood lead nutrition trends at SupplySide Global – https://www.nutraingredients.com/Article/2025/11/10/glp-1-longevity-and-mood-lead-nutrition-trends-at-supplyside-global
  4. Nutraceuticals World – Vitaquest 2026 dietary supplement trends report – https://www.nutraceuticalsworld.com/breaking-news/vitaquest-publishes-2026-dietary-supplement-trends-report/
  5. SupplySide SJ – 10 emerging supplement trends for 2026 – https://www.supplysidesj.com/market-trends-analysis/10-emerging-supplement-trends-2026
  6. Nutrition Insight – Trends in menopause supplements – https://www.nutritioninsight.com/trend-analysis/categories/trends-in-menopause-supplements.html
  7. Nutrition Insight – Gut health and digestive supplement trends – https://www.nutritioninsight.com/trend-analysis/ingredients/gut-health-digestive-supplement-trends.html
  8. BeautyMatter – The ingredient signals defining Vitafoods Europe 2026 – https://beautymatter.com/articles/the-ingredient-signals-defining-vitafoods-europe-2026
  9. ConsumerLab – 2026 supplement popularity survey – https://www.consumerlab.com/news/2026-supplement-popularity-press-release/02-26-2026/
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